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brimonidine ophthalmic. The Brimonidine ophthalmic may also be used for purposes not listed in this medication guide.

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ALPHAGAN® P (brimonidine tartrate ophthalmic solution) 0.1% or 0.15%, sterile, is a relatively selective alpha-2 adrenergic receptor agonist (topical intraocular pressure lowering agent). The structural formula of brimonidine tartrate is: 5-bromo-6- (2-imidazolidinylideneamino) quinoxaline L-tartrate; MW= 442.24. The completed phase IIa study had a randomized, double-masked, sham-controlled design. It randomized 113 patients into 3 groups (2:2:1) to receive low-dose or high-dose Brimo DDS (brimonidine = 132 mcg and 264 mcg, respectively; formulated as 200 mcg or 400 mcg of brimonidine tartrate, respectively) or sham treatment in the study eye.
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Open-angle glaucoma and other causes of high pressure in the eye increase the risk Brimonidine tartrate is a commonly used eyedrop for short- and long-term lowering of intraocular pressure.
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